Monday, March 28, 2016

Effect of Coffee Added to a Polyethylene glycol plus Ascorbic acid Solution for Bowel Preparation prior to Colonoscopy.

Adding coffee to a standard bowel prep regimen of polyethylene glycol with ascorbic acid reduces the total volume required for proper bowel prep prior to colonoscopy. Total volume was reduced from 2L to 1.5L.  (J Gastrointestin Liver Dis. 2016 Mar;25(1):63-9.)
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Wednesday, May 20, 2015

Recurrence of retinal vein thrombosis with Pycnogenol® or Aspirin® supplementation: a registry study.

This study found that dietary supplementation with pycnogenol (50 mg twice a day) was superior to standard care or standard care + aspirin in preventing a recurrence of retinal vein thrombosis. No adverse side-effects were observed in the pycnogenol group.  (Panminerva Med. 2015 Sep;57(3):121-5.)
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Sunday, April 26, 2015

Aspirin in the perioperative period: a review of the recent literature.

This review recommends that: a) ASA may be safely discontinued perioperatively when it is being given for the primary prevention of cardiovascular disease; b) patients with coronary or carotid artery stents should continue to receive ASA perioperatively; c) there is no indication to initiate ASA in patients with stable ischemic heart disease perioperatively as risks outweigh the benefits; d) patients with a previous myocardial infarction or ischemic stroke on ASA for secondary prevention, ASA in most surgeries is well tolerated, but further study is required.  (Curr Opin Anaesthesiol. 2015 Apr 16.)
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Thursday, April 16, 2015

Aspirin blocks growth of breast tumor cells and tumor-initiating cells and induces reprogramming factors of mesenchymal to epithelial transition.

This laboratory study found that aspirin showed a strong beneficial effect in the prevention of breast carcinogenesis.  (Lab Invest. 2015 Apr 13)
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Friday, March 20, 2015

Monday, March 9, 2015

Early and late effects of high- versus low-dose Angiotensin receptor blockade on renal function and outcomes in patients with chronic heart failure.

High doses of angiotensin receptor blockade with losartan (150 mg vs 50 mg per day) was associated with a decreased mortality rate, in spite of an increased risk of worsening renal function.  (JACC Heart Fail. 2015 Mar;3(3):214-23.)
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Monday, January 12, 2015

The Global Problem of Obesity

BACKGROUND: In 2010, overweight and obesity were estimated to cause 3·4 million deaths, 3·9% of years of life lost, and 3·8% of disability-adjusted life-years (DALYs) worldwide.

METHODS: a systematic review was performed.

FINDINGS: Worldwide, the proportion of adults with a body-mass index (BMI) of 25 kg/m(2) or greater increased between 1980 and 2013 from 29% to 37% in men, and from 30% to 38% in women. In 2013 in developed countries, 24% of boys and 23% of girls were overweight or obese.

INTERPRETATION: obesity has become a major global health challenge. No national success stories have been reported in the past 33 years.

Lancet. 2014 Aug 30;384(9945):766-81

Sunday, November 23, 2014

Smoking in Adolescent Males After Incarceration

Factors associated with smoking among adolescent males prior to incarceration and after release from jail: a longitudinal study.
BACKGROUND: The prevalence of cigarette smoking among incarcerated adult men and women is three-four times higher than in the general population, ranging from 70-80%. However, little is known about factors associated with smoking among incarcerated adolescents

QUESTION: what factors are associated with smoking among adolescent males prior to incarceration and one year after their release from jail?

METHODS: a database review was performed of data obtained from the "Returning Educated African-American and Latino Men to Enriched Neighborhoods" study. Differences between smokers and non-smokers were obtained at the time of their incarceration and one year after their release.

RESULTS: Prior to incarceration, 62% of the young men reported smoking. One-year after release, 69% reported smoking.

Factors associated with smoking prior to incarceration were:
  • foster care history
  • not living with parents
  • not attending school
  • drug sales
  • number of sex partners
  • gang involvement
  • current drug charges
  • number of prior arrests

Factors associated with smoking one year after release from jail:
  • foster care history
  • number of prior arrests

Subst Abuse Treat Prev Policy. 2013;8(1):37